Publications by authors named "N Schnepf"
Background: Cytomegalovirus (CMV) induces multi-organ pathogenesis in hematopoietic stem cell transplant (HSCT) and kidney transplant (KT) recipients. Effective management involves systematic monitoring for CMV reactivation by quantitative real-time PCR, allowing timely preemptive intervention. However, the optimal blood compartment for CMV surveillance remains undetermined.
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- The Omicron variant of SARS-CoV-2 has over 50 mutations that may increase transmission and evade immune responses from vaccines or prior infections.
- A study compared viral loads in saliva and nasopharyngeal swabs (NPS) during the Alpha, Delta, and Omicron waves, finding lower Ct values in NPS, but higher viral loads in saliva for Omicron.
- The results suggest that current diagnostic methods may need updates to better detect new variants like Omicron, highlighting the need for refined screening strategies.*
VIROLOGICAL ASPECTS, DIAGNOSTIC TOOLS AND VARIANTS OF SARS-COV-2 SARS-CoV-2 is an enveloped non-segmented linear single-stranded positive RNA virus. The envelope carries the protein spike (S) which recognizes the ACE2 receptor on the target cell and allows entry of the virus. The numerous mutations on the S protein are at the origin of a great genetic diversity, involved in the species barrier and the escape from neutralizing antibodies.
View Article and Find Full Text PDFA seafloor geomagnetic observatory in the northwest Pacific has provided very long vector geomagnetic time-series. It was found that the time-series include significant magnetic signals generated by a few giant tsunami events including the 2011 Tohoku Tsunami. Here we report that the tsunami-generated magnetic fields consist of the weak but first arriving field, and the strong but second arriving field-similar to the P- and S-waves in seismology.
View Article and Find Full Text PDFWe report a multidrug-resistant urogenital and pharyngeal infection with ceftriaxone resistance and intermediate resistance to azithromycin in a heterosexual woman in her 20s in France. Treatment with ceftriaxone plus doxycycline failed for the pharyngeal localisation. Whole-genome sequencing of isolate F90 identified MLST, NG-MAST ST, NG-STAR, and relevant resistance determinants.
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