Publications by authors named "N Sawicka-Gutaj"

Background: Saliva could be an attractive alternative to blood for assessing thyroid hormonal function.

Objectives: Our goal was to determine if the levels of thyroid hormones in saliva can accurately reflect a person's thyroid status and if they consistently correlate with the levels of the same hormones in the blood.

Design: We conducted a cross-sectional study.

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  • * A study analyzed medical records between January 2015 and December 2022, finding that 77.36% of preoperative male patients had HH, but this decreased to 58.49% post-surgery, along with significant increases in testosterone levels.
  • * The research suggests that younger patients with macroadenomas and hyperprolactinemia are more prone to preoperative HH, and about 30% may see hormone normalization after neurosurgical intervention.
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  • - The study examined the role of leptin receptor isoforms in adrenal tumors by analyzing 96 patients who had undergone adrenalectomy, comparing their tumor tissues to healthy controls.
  • - Findings showed that LepR1 expression was significantly lower in carcinoma patients compared to those with benign tumors, indicating its potential as a diagnostic marker.
  • - Additionally, certain isoforms (LepR3 and LepR6) were linked to overall survival rates, while others (LepR2, LepR4, and LepR5) were associated with cortisol levels, suggesting they could be useful prognostic indicators.
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Elevated immunoglobulin G4 (IgG4) serum antibodies are an important feature of IgG4-related disease. However, IgG4 antibodies can play a role in autoimmune thyroid disorders. In this study, we aimed to evaluate the impact of serum IgG4 levels on clinical features of Graves' disease (GD).

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Purpose: The imbalance of thyroid hormones affects the metabolic activity of various tissues, including periodontium. Also, autoimmune diseases present an increased tendency to suffer from periodontal disease. Therefore, our systematic review was designed to answer the question "Is there a relationship between thyroid diseases and periodontal disease?".

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