Applications of in silico methods to analyze the toxicity and estrogen receptor-mediated properties of plant-derived phytochemicals.

A myriad of phytochemicals may have potential to lead toxicity and endocrine disruption effects by interfering with nuclear hormone receptors. In this examination, the toxicity and estrogen receptor-binding abilities of a set of 2826 phytochemicals were evaluated. The endpoints mutagenicity, carcinogenicity (both CAESAR and ISS models), developmental toxicity, skin sensitization and estrogen receptor relative binding affinity (ER_RBA) were studied using the VEGA QSAR modeling package.

Isolation, characterization and docking studies of synergistic estrogen receptor a anticancer polyphenols from (Wt.) Walp.

Aim: This study aims to isolate, characterize, and evaluate of anticancer polyphenols from different parts of .

Materials And Methods: The polyphenols were isolated by standard protocol and characterized using Fourier-transform infrared (FT-IR), High performance liquid chromatography - Photodiode array detector coupled with Electrospray ionization - mass spectrometry (MS/MS). The compounds were elucidated based on retention time and molecular ions () either by [M+H]/[M-H] with the comparison of standard phenols as well as ReSpect software tool.

Documentation of ethnomedicinal information and antimicrobial validation of used by Yanadi tribe of Ganugapenta village, Chittoor district, Andhra Pradesh, India.

Aim: This study aimed to document the traditional knowledge of medicinal plants and antimicrobial validation of used by Yanadi tribe of Chittoor district, Andhra Pradesh, India.

Materials And Methods: The study was mainly focused on documentation of medicinal plants used by Yanadi tribe to treat different diseases with a standard questionnaire. These plants were cross-checked in Dr.

Biological synthesis of silver nanoparticles from Adansonia digitata L. fruit pulp extract, characterization, and its antimicrobial properties.

Aim: In the present study, we report a cost-effective, eco-friendly, and an efficient alternative method for large scale production of silver nanoparticles (AgNPs) from Adansonia digitata fruit pulp extract. The study mainly focused on the synthesis, characterization, and antimicrobial properties of AgNPs.

Materials And Methods: Synthesis of AgNPs with the help of standard protocol and characterized by ultraviolet (UV)-vis spectrophotometry, Fourier transform infra-red (FTIR), X-ray diffractometer (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM) with EDAX, transmission electron microscopy (TEM) and explore their potential growth inhibitory effect on 07 bacterial and 05 fungal pathogens.

Ethnomedicinal studies on plants used by Yanadi tribe of Chandragiri reserve forest area, Chittoor District, Andhra Pradesh, India.

Aim: Ethnomedicinal studies on medicinal plants used by Yanadi tribe of Chandragiri reserve forest area are documented during the period of 2014-2015. The study is mainly focused on medicinal importance of plants used by Yanadi tribe to treat various ailments.

Materials And Methods: The information collected on treated ailments, part used, preparation, combination, and addition of ingredients to prepare herbal medicines with the help of standard questionnaire.