Publications by authors named "N Sarid"
Article Synopsis
- Pancytopenia is a condition characterized by low levels of red and white blood cells as well as platelets, and diagnosing it can be complex due to various potential causes.
- The text discusses a rare case of a 53-year-old man experiencing myxedema coma, a severe form of untreated hypothyroidism, which led to his pancytopenia symptoms, including confusion and unstable vital signs.
- The patient was treated with intravenous levothyroxine and other supportive measures, resulting in improved health and normalized blood counts, highlighting the importance of recognizing myxedema coma in older patients who may not have regular healthcare access.
Article Synopsis
- Air embolism is a serious risk during central venous catheter (CVC) removal, often overlooked by less experienced healthcare workers, highlighting the need for better training and guidelines.
- A survey showed that one-third of respondents were unaware of air embolism risks, and many did not follow established protocols during CVC extraction.
- The study found that less experienced staff, particularly interns, had significantly lower knowledge about preventing air embolism, stressing the importance of hospital protocols and education for safety.
Article Synopsis
- * In the phase 2 trial, 20 patients received anti-CD19 CAR-T therapy combined with nivolumab, which was found to be safe; results showed an impressive 84% overall response rate and notable progression-free and overall survival rates at both 6 and 12 months.
- * Although CAR-T cell expansion was similar in patients eligible and ineligible for nivolumab, those eligible had a higher proportion of specific beneficial immune cell types, indicating that further
Background: Elderly patients account for nearly 70% of all primary central nervous system lymphoma (PCNSL) cases. They cannot tolerate aggressive treatment and have poor prognosis with a median overall survival (OS) of less than 2 years and progression-free survival (PFS) of 6-16 months. Ibrutinib penetrates the blood-brain barrier and has shown activity in PCNSL.
View Article and Find Full Text PDFPathogenic variants in LRBA, encoding the LPS Responsive Beige-Like Anchor (LRBA) protein, are responsible for recessive, early-onset hypogammaglobulinemia, severe multi-organ autoimmunity, and lymphoproliferation, with increased risk for malignancy. LRBA deficiency has a wide clinical spectrum with variable age of onset and disease severity. Three apparently unrelated patients with LRBA deficiency, of Georgian Jewish descent, were homozygous for LRBA c.
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