Publications by authors named "N Salbiah"
Primary prostatic melioidosis is a rare presentation of melioidosis even in melioidosis endemic areas. We report a case of a 58-year-old man with underlying diabetes mellitus who presented with a 5-day history of high-grade fever associated with lower urinary tract symptoms. Suprapubic tenderness and tender prostatomegaly were noted on examination.
View Article and Find Full Text PDFIntroduction: Coagulase-negative staphylococci (CoNS) is often considered as a culture contaminants but it can potentially be pathogenic to patients with risk factors. A combination of species identification and clinical criteria has been suggested in determining true CoNS bacteraemia.
Objectives: To identify the species distribution, antibiotic susceptibility patterns and clinical profiles of CoNS isolated from blood cultures among paediatric patients in Hospital Kuala Lumpur (HKL).
Article Synopsis
- Dengue is a viral disease transmitted by mosquitoes, with four different serotypes, and has been affecting tropical and subtropical regions for many years, including Malaysia where all serotypes can coexist.
- A study between 2010-2012 in Klang Valley analyzed serum samples from dengue patients to identify prevalent serotypes and any mutations linked to increased virus virulence.
- The findings indicated that Dengue-1 was the most common serotype, with high genetic similarity among isolates, and severe dengue cases showed a distinct mutation from non-severe cases, linking them to earlier outbreak strains in Malaysia.
This study was conducted to detect the presence of heterogenous vancomycin-intermediate Staphylococcus aureus (heteroVISA) among MRSA isolates in a major hospital. Forty-three MRSA isolates with vancomycin MIC 2 microg/ml collected in 2009 was screened for heteroVISA using Etest Glycopeptide Resistance Detection (GRD) and confirmed by population analysis profile-area under curve method. The genetic relatedness of heteroVISA strains with other MRSA was examined by pulsed-field gel electrophoresis (PFGE) method.
View Article and Find Full Text PDFArticle Synopsis
- A 64-year-old patient with bacteraemia didn't improve on vancomycin treatment, even though their MRSA strain was sensitive to it at an MIC of 2 microg/mL.
- Electron microscopy revealed that the MRSA isolate had a thickened cell wall, which is a key difference compared to other MRSA strains with lower vancomycin MICs.
- This thickening may contribute to the patient's lack of response to the antibiotic, highlighting a potential resistance mechanism.