Publications by authors named "N Sakly"
Article Synopsis
- Human Aichi virus 1 (AiV-1) is a picornavirus linked to gastroenteritis and is found frequently in environmental waters, indicating potential fecal contamination.
- Recent research examined 450 water samples from a Tunisian drinking water treatment plant and Sidi Salem dam, revealing 18.9% tested positive for AiV-1 with varying viral loads throughout different treatment stages.
- The presence of infectious AiV-1 particles poses a public health risk, and the study highlights the effectiveness of the integrated cell culture approach combined with quantitative molecular detection (ICC-RT-qPCR) for monitoring viruses in water.
Article Synopsis
- Research on the microbiota-gut-brain axis in autism has largely focused on bacteria, with fungi being underexplored, prompting a study on fungal involvement in Tunisian children with autism spectrum disorder.
- The study involved fecal sample analysis from 28 autistic children and 46 controls; they identified fungal isolates and tested their antifungal susceptibility and virulence factors.
- Results showed a significant presence of fungi in both groups, with specific antifungal resistance and virulence traits in the isolates, indicating a potential link between gut fungi and autism that warrants further investigation.
Background: Even though anti-neutrophil cytoplasmic antibodies (ANCA) are frequently linked to ANCA associated vasculitis (AAV), it's important to understand that other illnesses, including lung diseases, can also manifest as ANCA positivity. Finding the incriminated pathology might be difficult.
Aim: To report four ANCA-associated cases with a diagnosis problem.
Increased Rheumatoid Factor production in patients with severe COVID-19.
Diagn Microbiol Infect Dis
July 2024
Background: Searching for Rheumatoid Factors (RF) in patients with coronavirus disease (COVID-19) has rarely been described.
Objectives: To investigate the association between RF isotypes (IgM, IgA, and IgG) and different clinical presentations of COVID-19 in a series of Tunisian patients.
Study Design: Eighty-two COVID-19 patients were enrolled in this study.