[Autoimmune reaction component in chronic pancreatitis: clinical and experimental study].

Unlabelled: The study was undertaken to identify the relationship between inflammatory and autoimmune processes in chronic pancreatitis and to determine the prognostic significance of autoantibodies to antigens of acinar cells and hepatocytes, immunoglobulin G1-4.

Materials And Methods: In 85 patients with CP (43 men, 42 women) were studied autoantibodies to antigens of acinar and liver cells, IgG1-4. Of these, 43 patients HP was characterized by complications (cysts, calcification, pseudotumoral form), 40 patients--HP without complications, 2 patients were diagnosed chronic autoimmune pancreatitis (CAP), confirmed histologically.

[The role of neuromediators and cytokines in pathogenesis of chronic pancreatitis of alcohol etiology].

Aim: To determine the role of acetylcholine (AC), serotonine (5-HT) and cytokines in progression and complications of chronic alcohol pancreatitis (CAP).

Material And Methods: 50 CAP patients were examined in the exacerbation, remission and complications of CAP (48 males, 2 females) aged 30-50 years. Control group consisted of 15 healthy subjects.

[Cholelithiasis and biliary pancreatitis: pathogenetic and clinical aspects].

The main pathogenetic and clinical aspects of the cholecystolithiasis and biliary pancreatitis beginning and progress are discussed, including the results of our investigations.

[A cytokine status in chronic alcoholic and biliary pancreatitis].

Aim: To determine characteristics of a cytokine status in chronic pancreatitis (CP) depending on etiological factor, stage of the disease, complications, therapy. Material and methods. 72 patients had chronic alcoholic pancreatitis (CAP), 38 patients--chronic biliary pancreatitis (CBP).