[A comparative analysis of the antihypertensive activity of calcium antagonists and adrenoblockers in long-term treatment].

Essential hypertension stage II was treated by calcium antagonists, alpha- and beta-adrenoblockers in 362 patients. The drugs were compared for hypotensive efficiency at rest and exercise. A significant hypotensive effect was achieved in 81%, 58%, 44%, 43% and 37% of patients treated with labetalol, nifedipine, nadolol, propranolol, diltiazem, respectively.

[The efficacy of a 4-year course of drug treatment for patients with juvenile hypertension].

To evaluate the hypotensive efficacy and effects of some hypotensive drugs on the hemodynamics and concentration of testosterone in its blood plasma the authors examined 205 patients with juvenile hypertension (JH): main group--134 patients; comparison group--71 patients). Course treatment (1.5-2 months) with obsidan, niphedipin, verapamyl was carried out with nondrug treatment during intervals.

[The indices of the cerebral hemodynamics in patients with juvenile hypertension and different types of blood circulation].

A study of 100 patients with juvenile hypertension (JH) revealed a dependence between the character of changes of the cerebral vessel tone and type of central hemodynamics (TCH). Patients with the hypokinetic TCH show more frequently the vasospastic form of cerebral circulation (FCC) while the vasodilation FCC was observed rarer. The vasodilation FCC prevailed in patients with hyperkinetic TCH while the vasospastic was not observed.

[Radionuclide ventriculography in assessing left ventricular contractile function in patients with I-stage hypertension].

The general and local ejection fractions (EF) of the left ventricle were studied in 112 patients with grade I hypertensive disease and in 20 practically healthy persons at rest and during static isometric loads. At rest general and local EF were diverse. During loads both reduction and increase of general EF were observed.

[Effect of the treatment on hemodynamic indicators and plasma testosterone level in patients with juvenile hypertension].

The effect of anapriline, corinfar and reserpine on parameters of hemodynamics and plasma testosterone was evaluated in 60 juvenile hypertension patients who achieved pronounced hypotensive response. It was established that the level of sex hormones tended to diminution by the end of the treatment month 1 or 2, this drop being more noticeable in reserpine administration. Basing on this evidence it would be beneficial for patients suffering from juvenile hypertension in need of chemotherapy to take courses of the above drugs.