Publications by authors named "N S Swamy"
Berberine, an isoquinoline alkaloid derived from various medicinal plants, emerges as a potential therapeutic agent against diverse human diseases. It has particularly shown notable anticancer efficacy against breast, colorectal, lung, prostate, and liver cancer. Berberine results in inhibition of cancer cell proliferation, induction of apoptosis, and suppressing angiogenesis, positioning it as a versatile, multitargeted therapeutic tool against cancer.
View Article and Find Full Text PDFSingle-Center Retrospective Review of Standard Versus Minimal Monitoring for Hepatitis C Direct Acting Antiviral Therapy.
J Am Pharm Assoc (2003)
October 2024
Background: Highly effective direct acting antiviral (DAA) therapies have transformed the landscape of Hepatitis C Virus (HCV) treatment. However, there continues to be limited data regarding the efficacy and safety of required in-person clinic visits (standard monitoring) versus completely telehealth clinic visits (minimal monitoring) during HCV therapy, which could delay practice adoption.
Objectives: This study aimed to assess the rates of undetectable HCV RNA in sustained viral load 12 weeks after therapy (SVR12) in standard versus minimal monitoring approaches during DAA.
Article Synopsis
- - The study reviews the effectiveness of an endoscopic posterior approach for decompressing the cervical spinal cord and roots in 229 patients, particularly focusing on those with myelopathy or radiculopathy caused by posterior compression.
- - Results showed significant improvement post-surgery, with the average Nurick grade (a measurement of neurological impairment) dropping from 2.72 to 0.78, indicating better outcomes in patients who started with lesser impairments.
- - While the endoscopic method was found to be safe with few complications, the study has limitations, such as being retrospective and conducted at a single center, suggesting the need for further multicenter research to confirm findings.
Background: Practicing neuroendoscopic skills like hand-eye coordination is mandatory before embarking on actual surgeries. Synthetic models are able alternatives for cadavers and animals. Presently available models in the literature are either very costly or lack a feedback mechanism, which makes training difficult.
View Article and Find Full Text PDFBackground: Endoscopic procedures are useful in chronic subdural hematoma especially when there are septations, solid/organized hematoma, and the presence of bridging or neovessels in the cavity. Visualizing the distal hematoma cavity by a rigid scope is challenging in large and curved ones due to the hindrance by the brain surface. Combining rigid endoscopy and brain retractor can overcome this limitation.
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