[Clinico-genealogical study of microcirculation in diabetes mellitus type 1].

Altogether 60 patients with type I diabetes mellitus and their 29 relatives were examined. Diabetic microangiopathies were diagnosed in 29 patients, in 31 they were not found. Among relatives of the 1st degree of relationship 16 persons were with type I diabetes mellitus with angiopathies, 13 persons without angiopathies.

[Evaluation of the metabolizing function of the liver in thyrotoxicosis using the antipyrine test].

A study was made of pharmacometabolizing liver function in 73 patients with thyrotoxicosis of various degree and duration. The antipyrine test was used to assess pharmacometabolizing liver function. In thyrotoxicosis of moderate severity and in severe forms with the period of the disease over 1 year the half-life increased and antipyrine clearance decreased.

Content of thyroid hormones in human and animal milk and in cow milk based infant formulas.

The concentration of thyroxine (T4), triiodothyronine (T3), thyroxine binding globulin (TBG) as well as thyroxine binding to proteins (TBP) and free thyroxine index (FTI) were measured in human milk. In addition, the concentration of T4 in milk of rats, rabbits and cows and in cow milk based infant formulas was measured. It was found that the concentration of T4 and T3 in human milk or that of T4 in rat and rabbit milk is much higher than in corresponding colostrum.

[Lactation regulation and the content of thyroid hormones in the milk of parturients and components of infant food formulas].

The content of folliculostimulating (FSH), luteinizing (LH), thyrotropic (TTH) hormones and prolactin was studied in the blood serum of pregnant women and puerperants; also the thyroxin (T4), triiodthyronin (T3), thyroxin-binding globulin (TBG) levels, and the thyroxin-binding capacity of proteins and free T4 index were determined in the blood serum and milk of puerperants during the first week of lactation. The blood serum FSH, LH, TTH and prolactin concentrations underwent definite changes connected with physiological reconstruction of the organism at these periods. The milk T4 and T3 levels showed a sharp elevation by the 6th day of lactation, this correlating with the changes in the blood serum.