Publications by authors named "N S Petersen"
Trauma and the default mode network: review and exploratory study.
Front Behav Neurosci
December 2024
While PTSD continues to be researched in great depth, less attention has been given to the continuum of traumatic responses that resides outside this diagnosis. This investigation begins with a literature review examining the spectrum of responses through the lens of the default mode network (DMN). To build upon this literature, a systematic exploratory study was incorporated, examining DMN-related neuropsychological functioning of 27 participants (16 trauma-exposed, and 11 non-trauma-exposed), with a subset (15 participants) completing neuroimaging.
View Article and Find Full Text PDFArticle Synopsis
- Magnetotactic bacteria (MTB) utilize both magnetic field alignment and a chemotactic response to navigate to their ideal living depths in environments with varying chemical compositions.
- Current models of magneto-aerotaxis don’t accurately explain why some MTB are found below the oxic-anoxic interface or how different groups coexist at these depths despite their opposing magnetic polarities.
- A proposed new model suggests that MTB's magnetotactic behavior is influenced by specific gradients of oxygen and other substances, allowing them to navigate effectively across these gradients and adapt to varied ecological environments.
Article Synopsis
- A study evaluated the safety and efficacy of endovascular thrombectomy in patients with acute large-vessel occlusion and tandem lesions, focusing on those with low (0-5) and high (6-10) Alberta Stroke Program Early Computed Tomography Scores (ASPECTS).
- The analysis included 691 patients, revealing that those with low ASPECTS had significantly lower odds of achieving a favorable functional outcome (mRS 0-2) and higher odds of suffering symptomatic intracranial hemorrhage compared to those with high ASPECTS.
- The researchers concluded that endovascular thrombectomy may lead to poorer functional recovery in patients with tandem lesions and low ASPECTS, particularly in the
Objective: In this study, we piloted the use of continuous 24-hour blood pressure (BP) monitoring in postpartum patients with preeclampsia with severe features.
Study Design: We measured continuous BP for up to 24 hours using finger plethysmography. We also used an oscillometric device to measure brachial BP per usual clinical protocol (intermittent BP) during the same monitoring period.
Article Synopsis
- Sleep and arousal disorders are common, influenced by the locus coeruleus and wake-promoting neurons in the ventral periaqueductal gray (vPAG), yet the exact mechanisms of wakefulness remain unclear.
- The study employs genetic techniques, calcium imaging, and behavioral tests in mice to examine how astrocytic alpha-1 adrenergic receptors (αARs) affect neuron activity through adenosine signaling.
- Results show that activating αARs boosts calcium activity and excitability in vPAG neurons, while blocking adenosine receptors hampers this wake-promoting function, highlighting the essential role of astrocytic αARs in maintaining arousal.