Structure, properties, and decomposition in biological systems of a new nitrosyl iron complex with 2-methoxythiophenolyls, promising for the treatment of cardiovascular diseases.

A new promising binuclear tetranitrosyl iron complex with 2-methoxythiophenolyl of the composition [Fe(CHOS)(NO)] (complex 1), which acts on the therapeutic targets of cardiovascular diseases, guanylate and adenylate cyclase, has been synthesized. X-ray diffraction data show the presence of two isoforms of complex 1; according to quantum chemical calculations, the structure of only the trans isomer is stable in solutions. The processes of transformation of complex 1 in DMSO, in aqueous solutions, as well as in the presence of bovine serum albumin, reduced glutathione, and mucin were studied.

Synthesis of a tetranitrosyl iron complex with unique structure and properties as an inhibitor of phosphodiesterases.

A novel neutral tetranitrosyl iron complex {[Fe(HO)][FeR(NO)]}·4HO (1) with R = 5-(3-pyridyl)-4-1,2,4-triazole-3-thiolyls (CHNS), which is a supramolecular ensemble, has been synthesized and studied. As follows from X-ray diffraction analysis, this is an octahedral Fecomplex (Lewis acid) with two monoanionic dinitrosyl groups [FeR(NO)] (Lewis base) and 4 water molecules as the ligands. As follows from Mössbauer spectra, the coordinating Fe ion is in a low-spin state = 0, and the dinitrosyl Fe ion is in a low-spin state = 1/2.

A nitrosyl iron complex with 3.4-dichlorothiophenolyl ligands: synthesis, structures and its reactions with targets - carriers of nitrogen oxide (NO) .

In this work, a new binuclear nitrosyl complex with 3.4-dichlorothiophenolyl ligands [Fe(SCHCl)(NO)] has been synthesized. Nitrosyl iron complexes (NICs) are systems for the storage and delivery of NO in the body.

First crystal structure of an Fe(III) anionic complex based on a pyruvic acid thiosemicarbazone ligand with Li: synthesis, features of magnetic behavior and theoretical analysis.

The iron(III) anionic complex based on a pyruvic acid thiosemicarbazone ligand with the lithium cation Li[Fe(thpy)]·3HO (1) has been synthesized and characterized by FTIR spectroscopy, powder and single crystal X-ray diffraction, direct current magnetic susceptibility measurements, and Fe Mössbauer spectroscopy. Moreover, the molecular structure of the [Fe(thpy)] anion has been determined for the first time. The [Fe(thpy)] units in the triclinic 1̄ lattice of 1 are assembled into layers parallel to the plane.

(S)-(-)-(2-MeBu)N(Pr)₂MeI salt as template in the enantioselective synthesis of the enantiopure two-dimensional (S)-(-)-(2-MeBu)N(Pr)₂Me[ΛMnΔCr(C₂O₄)₃] ferromagnet.

We describe herein the synthesis of (rac)- or enantiopure (S)-(-)-(2-MeBu)N(Pr)₂MeI ammonium salts. These racemic and enantiopure ammonium salts were used as cationic templates to obtain new two-dimensional (2D) ferromagnets [(rac)-(2-MeBu)N(Pr)₂Me][MnCr(C₂O₄)₃] and [(S)-(-)-(2-MeBu)N(Pr)₂Me][ΔMnΛ nCr(C₂O₄)₃]. The absolute configuration of the hexacoordinated Cr(III) metallic ion in the enantiopure 2D network was determined by a circular dichroism measurement.