Publications by authors named "N S Nadkarni"
Chronic stress is a major contributor to the development of major depressive disorder, one of the leading causes of disability worldwide. Using a model of repeated social defeat stress in mice, we and others have reported that neuroinflammation plays a dynamic role in the development of behavioral deficits consistent with social avoidance and impaired reward responses. Animals susceptible to the model also exhibit hypomyelination in the medial prefrontal cortex, indicative of changes in the differentiation pathway of cells of the oligodendroglial lineage (OLN).
View Article and Find Full Text PDFBackground: The relationship between subtle cognitive decline and Alzheimer's disease (AD) pathology as measured by biomarkers in settings outside of specialty memory clinics is not well characterized.
Objective: To investigate how subtle longitudinal cognitive decline relates to neuroimaging biomarkers in individuals drawn from a population-based study in an economically depressed, small-town area in southwestern Pennsylvania, USA.
Methods: A subset of participants without dementia (N = 115, age 76.
This capsule review is a discussion of myofascial pain syndrome in small animals. The history of myofascial pain syndrome is discussed as well as facts and theories behind the aetiology and treatment of this syndrome. Diagnostic techniques are both discussed and illustrated.
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- Vascular epiphytes in tropical montane cloud forests are at risk due to climate change, as rising cloud bases limit moisture and atmospheric inputs, particularly for those growing on isolated pasture trees.
- Researchers studied the water relations of these epiphytes in Monteverde, Costa Rica, measuring sap velocity and microclimate variables across different seasons and sites.
- Results showed that drought conditions increased the turgor loss point of the epiphytes, with significant correlations between microclimate and sap velocity in the wet season, highlighting potential vulnerabilities in pasture trees compared to those in the forest.
Ischemic stroke is a leading cause of disability worldwide. While much of post-stroke recovery is focused on physical rehabilitation, post-stroke dementia (PSD) is also a significant contributor to poor functional outcomes. Predictive tools to identify stroke survivors at risk for the development of PSD are limited to brief screening cognitive tests.
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