Neurosci Biobehav Rev
December 2024
Acomys cahirinus (referred to as "acomys" in this article) is a precocial rodent, born well-developed and mobile, capable of feeding independently and escaping predators shortly after birth. Notable for its advanced regenerative abilities and menstrual cycle, acomys serves as a unique model for studying diverse aspects of physiology and neuroscience, including developmental and regenerative neuroscience. Despite its significance, only sporadic and unsystematic data on the structure and development of the acomys brain are available.
View Article and Find Full Text PDFRat strains differ in physiology, behavior, and recovery after central nervous system injury. To assess these differences, we compared the gross and local anatomy and neuromorphology of the lumbar spinal cord of the Wistar and Dark Agouti (DA) strains. The key findings include (i) distinct spatial relationships between vertebrae and spinal segments in the two strains; (ii) Wistar rats have larger volumes of spinal cord gray and white matter; (iii) DA rats have smaller total neuronal populations, thus indicating an expectation of smaller local neuronal populations; (iv) this expectation was confirmed for interneurons expressing calbindin 28 kDa.
View Article and Find Full Text PDFComplex neurophysiological and morphologic experiments require suitable animal models for investigation. The rabbit is one of the most successful models for studying spinal cord functions owing to its substantial size. However, achieving precise surgical access to specific spinal regions requires a thorough understanding of the spinal cord's cytoarchitectonic structure and its spatial relationship with the vertebrae.
View Article and Find Full Text PDFUsing anti-neurofilament H non-phosphorylated antibodies (SMI-32) as markers for the neuronal maturation level and Y channel responsible for motion processing, we investigated early postnatal development of the primary visual areas 17 and 18 in cats aged 0, 10, 14, and 34 days and in adults. Two analyzed parameters of SMI-32-immunolabeling were used: the total proportion of SMI-32-labeling and the density of labeled neurons. (i) The developmental time course of the total proportion of SMI-32-labeling shows the general increase in the accumulation of heavy-chain neurofilaments.
View Article and Find Full Text PDFis a unique Rodentia species with several distinctive physiological traits, such as precocial development and remarkable regenerative abilities. These characteristics render increasingly valuable for regenerative and developmental physiology studies. Despite this, the structure and postnatal development of the central nervous system in have been inadequately explored, with only sporadic data available.
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