Publications by authors named "N S Krivokhizhina"
Horm Cancer
December 2016
Article Synopsis
- Urinary steroid profiling (USP) was conducted in 139 patients, revealing distinct differences in androgen and glucocorticoid secretion between adrenocortical carcinoma (ACC) and adrenocortical adenoma (ACA) cases.
- High-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) detected increased levels of dehydroepiandrosterone (DHEA) and tetrahydro-11-deoxycortisol (THS) in a significant percentage of ACC patients.
- A diagnostic combination of specific hormone levels and ratios achieved 100% sensitivity and specificity for differentiating ACC from ACA, with additional features linked to 21-hydrox
