[The dynamics of developmental disorders of the brain in fetuses obtained from mothers consuming alcohol during pregnancy (14- to 15-week-old fetuses)].

By histological method cerebral development was studied in 3 fetus obtained after 14, 14 and 15 weeks to gestation in the mothers abusing alcohol. The excessive plication, invagination and adhesions of the brain wall, porencephalia, abnormal hyperplasia and heterotopia of cells, as well as agenesis of plexus choroideus were detected. These finding were compared with the disturbances in 5- to 12-week-old embryos which had been earlier discovered by authors.

[Dysontogenesis of the brain of the progeny born to mothers drinking alcohol during pregnancy].

A study was made of the development of the brain from 44 embryos (5-12 weeks) and 1 fetus (14 weeks) obtained from mothers who used alcohol during pregnancy. 16 cases made up the control group. In 34 cases out of 45 (75.

[Development of embryonal brain synapses in the normal state and in maternal alcoholism].

Electron microscopy was used to study embryonal brains (n-10) of 7-12-week gestation from mothers abusing alcohol at the time of medical abortion. Control group consisted of 20 embryos from healthy women. The study group demonstrated delayed formation of synaptic structures, a great number of extrasynaptic contacts, sings of clear-type degeneration of some mature synapses.

[Various results of the study of medico-biological aspects of alcoholism in Siberia and Far East].

To study the dynamic changes in alcohol abuse, a new methodological approach has been developed which implies staged realization. Stage one was aimed at the search for integral clinical-dynamic characteristics as well as social and psychological properties to make identification of the clinical phenotype reliable. Stage II--at introduction of integral constitution-morphology indicators representative of the disease predisposition-stability.

[Neural tube dysraphia at the level of the midbrain in alcoholic embryopathy].

Forty-four 5-12-week embryos obtained from mothers who abused alcohol during pregnancy were examined for brain development. Six cases of dysraphia of the neural tube at the midbrain level were revealed. In two cases, it was defined as primary.