Background: The continuous research on minor depressive disorder is one of the pressing issues in the context of the COVID-19 pandemic. We studied the features of minor depressive disorder subtypes in conditions of the COVID-19 pandemic.
Materials And Methods: Sixty-two patients were observed with the administration of clinical follow-up research method.
The epidemiological situation in Tajikistan Republic deteriorated in the 1990s, when an influx of refugees from Afghanistan resulted in mass importation of and malaria to Khatlon region. The National Programme of Malaria Control was successful and malaria transmission was interrupted in 2009. .
View Article and Find Full Text PDFThe complications of tropical malaria were noted in 25 (9.4%) of 196 pediatric patients followed up. These included cerebral malaria in 8 (3%), severe hemolytic anemia in 15 (5.
View Article and Find Full Text PDFMed Parazitol (Mosk)
September 2011
The paper gives data on impaired cytokine status in children with tropical malaria. There have been heterodirectional changes in the level ofcytokines during the infectious process and in relation to the severity of the pathological process, which allow prediction of the course of tropical malaria. Correlations were found between the clinical and laboratory parameters and the level of proinflammatory cytokines, which provide evidence for an important role of inflammatory mediators in the clinical course of the disease.
View Article and Find Full Text PDFThe paper presents data on age-related cytokine dysregulation in children with tertian or tropical malaria infection. Immunological changes depended on the dynamics of the infectious process and the severity of the pathological one. The most pronounced changes were observed in a group of infants probably due to the functional immaturity of immunoregulatory mechanisms appearing as elevated levels of proinflammatory cytokines with a reduction in IFN-gamma, which suggest that Th-1 lymphocyte reactions are inhibited.
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