Clinical profile analysis of SARS-CoV-2 community infections during periods with omicron BA.2, BA.4/5, and XBB dominance in Hong Kong: a prospective cohort study.

Background: Existing studies on SARS-CoV-2 infection have mainly focused on severe clinical outcomes; understanding of the clinical severity profile of general community infections is poor. We aimed to assess and compare the clinical profiles of infections with SARS-CoV-2 omicron (B.1.

Organofunctionalized borotungstate polyoxometalates as tunable photocatalysts for oxidative dimerization of amines.

Organofunctionalized borotungstate Keggin polyoxometalates, ( BuN)H[HBWO(P(O)Ph)] (PBW), ( BuN)H[HBWO(As(O)Ph)] (AsBW), and ( BuN)[HBWO(PhSiOSiPh)] (SiBW), were synthesized and structurally characterized. Cyclic voltammetry showed that the electronic properties of the clusters are dependent on the nature of the appended main group atoms (P, As, or Si). The first reduction potentials were found to shift positively with respect to that of the unmodified parent species ( BuN)[BWO], with PBW showing the largest shift at +100 mV.

Sequence basis for selectivity of ephrin-B2 ligand for Eph receptors and pathogenic henipavirus G glycoproteins.

Ephrin-B2 (EFNB2) is a ligand for six Eph receptors in humans and regulates multiple cell developmental and signaling processes. It also functions as the cell entry receptor for Nipah virus and Hendra virus, zoonotic viruses that can cause respiratory and/or neurological symptoms in humans with high mortality. Here, we investigate the sequence basis of EFNB2 specificity for binding the Nipah virus attachment G glycoprotein over Eph receptors.