Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery.

Obesity is associated with low-grade inflammation and increased systemic oxidative stress. Roux-en-Y gastric bypass (RYGB) surgery is known to ameliorate the obesity-induced metabolic dysfunctions. We aimed to study the levels of natural antibodies in feces, before and 6 months after RYGB surgery in obese individuals with and without type 2 diabetes (T2D).

Gastrointestinal manifestations after Roux-en-Y gastric bypass surgery in individuals with and without type 2 diabetes.

Background: Roux-en-Y gastric bypass (RYGB) surgery is an effective treatment for obesity, which improves cardiovascular health and reduces the risk of premature mortality. However, some reports have suggested that RYGB may predispose patients to adverse health outcomes, such as inflammatory bowel disease (IBD) and colorectal cancer.

Objectives: The present prospective study aimed to evaluate the impact of RYGB surgery on cardiovascular risk factors and gastrointestinal inflammation in individuals with and without type 2 diabetes (T2D).

[Regional intraarterial chemoimmunotherapy in complex treatment of patients with colon cancer complicated by metastatic lesion of the liver].

Results of combined treatment of 48 colon cancer patients with metastases to the liver are analyzed. Efficacy of regional intraarterial chemoimmunotherapy with recombinant interleukine-2 (ronkoleukine) is evaluated. The results of the treatment demonstrate that regional intraarterial chemoimmunotherapy with recombinant interleukine-2 is a safe and promising method in combined treatment of advanced colon cancer, increases survival and improves quality of life.

[Two-stage policy of treatment of cholelithiasis complicated with choledocholithiasis].

Results of endo-surgical treatment in 81 patients with choledocholithiasis are analyzed. There were 60 women and 21 men aged from 24 to 77 years. It is demonstrated that inclusion of octreotid and dicetel in combined two-stage treatment of choledocholithiasis decreases the risk of pancreatitis and bleeding after endoscopic papillosphincterotomy, number of postoperative complications, hospital stay, cost of treatment and provides good cosmetic effect.

[Neutrophil and macrophage functional activity during the irradiation of an intestinal anastomosis with a low-intensity laser in the infrared spectral range].

The influence of different methods of treatment of intestinal anastomosis in rabbits (group 1: common single-row sutures; group 2: sutures treated with cyanacrylate glue CO-4; group 3: low-intensity laser irradiation through the skin in the infrared spectral range) on the phagocytic and oxidase activity of cells in the peritoneal washings and peripheral blood on days 2, 4 and 7 after the operation was studied. Laser irradiation of the suture was shown to produce a stimulating effect on the macrophagal-phagocytic system of the blood. The oxidase activity of phagocytes in peritoneal washings in the group of animals subjected to laser irradiation was considerably lower than in two other groups.