Publications by authors named "N S Dhalla"

Wound healing is an intricate process involving biological alterations in cellular integrity. Low-level laser therapy (LLLT) includes special features that speed up tissue regeneration and wound healing. The objective of this review is to examine the outcomes of photobiomodulation therapy in terms of healing.

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Article Synopsis
  • - Na-K ATPase is crucial for heart function, consisting of three subunits that help transport sodium and potassium ions, maintaining the balance of these cations in heart cells and influencing heart contractions.
  • - This enzyme also acts as a receptor for certain glycosides and steroids, regulating heart metabolism and cell survival, with its activity affected by various hormones through modifications of its associated protein, phospholemman.
  • - In heart failure, Na-K ATPase activity can change in different ways, leading to either adaptive mechanisms for maintaining function or issues like calcium overload and arrhythmias, ultimately impacting heart health based on the enzyme's isoform composition and oxidative stress.
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Dental implants are fixtures that replace a natural tooth that has been missing. The outcome depends on the safety and longevity of the bone-implant relationship. The process of direct and strong anchoring of an implant due to the surrounding bone tissue growing around it is called osseointegration.

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Vitamins are known to affect the regulation of several biochemical and metabolic pathways that influence cellular function. Adequate amounts of both hydrophilic and lipophilic vitamins are required for maintaining normal cardiac and vascular function, but their deficiencies can contribute to cardiovascular abnormalities. In this regard, a deficiency in the lipophilic vitamins, such as vitamins A, D, and E, as well as in the hydrophilic vitamins, such as vitamin C and B, has been associated with suboptimal cardiovascular function, whereas additional intakes have been suggested to reduce the risk of atherosclerosis, hypertension, ischemic heart disease, arrhythmias, and heart failure.

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Although -adrenoceptor ( -AR) signal transduction, which maintains cardiac function, is downregulated in failing hearts, the mechanisms for such a defect in heart failure are not fully understood. Since cardiac hypertrophy is invariably associated with heart failure, it is possible that the loss of -AR mechanisms in failing heart occurs due to hypertrophic process. In this regard, we have reviewed the information from a rat model of adaptive cardiac hypertrophy and maladaptive hypertrophy at 4 and 24 weeks after inducing pressure overload as well as adaptive cardiac hypertrophy and heart failure at 4 and 24 weeks after inducing volume overload, respectively.

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