Prevalence and descriptive epidemiology of esophageal atresia in the Russian Federation.

Background: This study examined the prevalence of esophageal atresia (EA) and the relationship between EA and demographic factors in the Russian Federation.

Methods: Data were obtained from a population-based congenital malformations registry across 14 years (2000-2013) in 24 regions of the Russian Federation and included cases of EA among live births and stillbirths.

Results: The total number of births was 6,478,706.

[[Epidemiological, Clinical and Genetic Characteristics of Anorectal Malformations (Review)].].

The review presents an analysis of current data on the epidemiology, etiology, clinical and genetic characteristics of congenital anorectal malformations (AM). According to international registers of congenital malformations prevalence of the AM varies from 2 to 5 per 10,000 births. There was no change in the prevalence over time of AM (absence of temporal trends).

[Genetic counseling in the Mental Health Research Center of the Russian Academy of Medical Sciences].

Current concepts on the role of genetic factors in the development of schizophrenia and on the relative risk for this disease and spectrum disorders are reviewed. An analysis of the results of genetic counseling of 120 subjects revealed that, comparing to other mental disorders, patients with schizophrenia or relatives, mostly those having a schizophrenic parent (40%) or spouse (25%), referred more frequently for a consultation. Most of the referrals (70%) had a high educational level.

A multifunctional system of the national genetic register.

The National (Federal) Russian Genetic Register operates as a multifunctional system. It is designed for finding solution to the following key problems: 1. Information provision to watch families having children with hereditary and congenital diseases.