H NMR with Partial Transition Selectivity.

H NMR has unique strengths, owing, for one, to H being the most sensitive NMR nucleus. However, the limited frequency range of H chemical shifts implies spectral crowding, leading to difficulties in assignment and interpretation of the spectra. Homonuclear broadband decoupling has been developed as a means of simplifying H NMR spectra but clearly leads to the inevitable and complete loss of precious information on homonuclear scalar couplings in solution state.

Preferential solvation of carbohydrates in water-trifluoroethanol mixtures: a solvent detected heteronuclear NMR approach.

The present study aims to establish a simple approach involving multi-field multinuclear longitudinal relaxation (R1) analysis of the solvents to decipher solute-solvent interactions during the solvation of model carbohydrates in aqueous trifluoroethanol (TFE) co-solvent systems (TFE:D2O). The behavior of D2O and TFE is monitored around β-CD (β-cyclodextrin) and glucose through R1D (2H) and R1F (19F), respectively. Correlation times (τc) are estimated for D2O and TFE for various % (v/v) compositions of TFE:D2O mixtures.

Magnetic resonance imaging of enhanced mobility of light non aqueous phase liquid (LNAPL) during drying of water wet porous media.

Visualization of NAPLs in multiphase systems in porous media is important for determining contaminant transport in the environment. In this study, magnetic resonance imaging (MRI) was used to confirm the recent observations of mobilisation of a light non aqueous phase liquid (LNAPL) trapped in wet sand under natural drying conditions of the wet porous medium. Visualization of LNAPL (motor oil) and water mobility during the drying of wet glass beads (0.

Assessment of the Role of 2,2,2-Trifluoroethanol Solvent Dynamics in Inducing Conformational Transitions in Melittin: An Approach with Solvent F Low-Field NMR Relaxation and Overhauser Dynamic Nuclear Polarization Studies.

2,2,2-Trifluoroethanol (TFE) is one of the fluoroalcohols that have been known to induce and stabilize an open helical structure in many proteins and peptides. The current study has benchmarked low-field F NMR relaxation and F Overhauser dynamic nuclear polarization (ODNP) by providing a brief account of TFE solvent dynamics in a model melittin (MLT, an antimicrobial peptide) solution with a TFE-DO cosolvent mixture at pH 7.4.

Motional Dynamics of Halogen-Bonded Complexes Probed by Low-Field NMR Relaxometry and Overhauser Dynamic Nuclear Polarization.

Halogen bonding is a subject of considerable interest owing to wide-ranging chemical, materials and biological applications. The motional dynamics of halogen-bonded complexes play a pivotal role in comprehending the nature of the halogen-bonding interaction. However, not many attempts appear to have been made to shed light on the dynamical characteristics of halogen-bonded species.