Publications by authors named "N S Buzhak"

The hormonal function of the hypophysis and thyroid (TTG, T3, T4) and its dependence on hepatobiliary function, examined by hepatobiliscintigraphy, were studied by radioimmunoassay in 71 patients with chronic opisthorchiasis and in 18 chronic carriers of Salmonella typhi. in both groups. The decrease of T3 and T4 in the presence of normal TTG level was found.

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The effect of two anthelmintics--biltricide and chloxyl--on the immune status has been compared in patients with chronic opisthorchiasis. It has been established that in using chloxyl there is a more marked and persistent imbalance of immunoregulatory T-lymphocyte subpopulations (T mu-helpers-inducers and T gamma-suppressors-effectors).

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The anthelminthic agents chloxylum and prasiquantel were examined for their effects in patients with an above 5-year history of Opisthorchis invasion. The van de Kamer procedure revealed that chloxylum produced an inhibitory effect on absorption of d-xylose and fat. Prasiquantel failed to impair the absorptive function of the small intestine.

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Most immunological characteristics became practically normal 7-9 months after a single chloxyl treatment course in patients with chronic cholecystocholangitic opisthorchiasis. The patients who required repeated chemotherapy showed more profound and steady immune disturbances.

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