Enterovirus 71-Associated Infection in South Vietnam: Vaccination Is a Real Solution.

Hand-foot-and-mouth disease (HFMD) is the most common enteroviral infection in South-East Asia. When evaluating the role of enterovirus 71 (EVA71) as an etiological agent of infectious disease in South Vietnam, we revealed a high proportion of EVA71 among identified species A enteroviruses found in 3542 samples from HFMD cases; 125 samples from cases of enteroviral meningitis; and 130 samples from acute flaccid paralysis (AFP) cases. These represent 50%, 54.

Cases of Acute Flaccid Paralysis Associated with Coxsackievirus A2: Findings of a 20-Year Surveillance in the Russian Federation.

Surveillance for acute flaccid paralysis syndrome (AFP) in children under 15 is the backbone of the Global Polio Eradication Initiative. Laboratory examination of stool samples from AFP cases allows the detection of, along with polioviruses, a variety of non-polio enteroviruses (NPEV). The etiological significance of these viruses in the occurrence of AFP cases has been definitively established only for enteroviruses A71 and D68.

[Risk of introduction and spread of polioviruses in closed-type child-care facilities].

Aim: Compare frequency of isolation of polioviruses in children living in closed-type facilities (orphanages) before and after the change in poliomyelitis vaccination scheme.

Materials And Methods: Feces samples of 207 children from 5 orphanages during immunization with oral poliomyelitis vaccine (OPV) and of 259 children from 4 orphanages during vaccination with inactivated poliomyelitis vaccine (IPV) were studied. Isolation and identification of polioviruses was carried out according to WHO recommendations.

[Group enterovirus infection due to coxsackievirus A16 in Northwestern Russia].

Aim: Study features of epidemic process and etiology of oral cavity and limb enterovirus exanthema group diseases in a number of territories of Northwestern Russia.

Materials And Methods: Isolation and identification of non-poliomyelitis enteroviruses from material of patients was carried out according to WHO recommendations. Phenotyping and phylogenetic analysis of enteroviruses was carried out.

[The role of epidemiologic surveillance of migrants in the system of poliomyelitis control].

Aim: Analysis of results of virological study of material from children of migrants and evaluation of intensity of immunity against polioviruses in these children.

Materials And Methods: 1668 feces samples from patients with acute flaccid paralysis and contact individuals and 479 feces samples from healthy children from families of migrants, as well as 1012 blood sera of children aged 3 - 4 and 14 - 15 years living in the same territory of Russia, and 169 blood sera of children of migrants were studied. Polioviruses and non-polio enteroviruses were isolated by standard procedures recommended by WHO in 3 cell cultures - RD, L20B and Hep-2.