Platelet-rich plasma effects on in vitro cells derived from pediatric patients with andrological diseases.

Undescended testis and testicular torsion represent two frequent andrological diseases that affect the pediatric age. Despite these testicular disorders having different causes, they both negatively influence fertility in adulthood mainly due to the accumulation of reactive oxygen species (ROS), which represents the primary molecular damage underlying their long-term effects. The gold standard of treatment for both pathologies is surgery; however, it cannot guarantee an optimal fertility outcome in all clinical cases, underscoring the need to identify effective adjuvant therapies that may target the augmented ROS levels.

The Integrated Multidisciplinary Pathway for Large-Scale Management of Dyslipidemia in High-Risk Patients (ENNA) Project: Rationale and Project Design.

Atherosclerotic cardiovascular disease is a leading cause of morbidity and mortality globally, significantly influenced by modifiable risk factors, particularly hypercholesterolemia. Despite the availability of effective lipid-reducing drugs, achieving the low-density lipoprotein cholesterol (LDL-C) target levels remains a significant challenge in clinical practice, contributing to persistently high rates of cardiovascular events. The intEgrated multidiscipliNary pathway for large-scale maNagement of dyslipidemiA in high-risk patients (ENNA) Project was designed to address the alarming rates of suboptimal lipid management in patients at great and very great risk in the province of Enna, Sicily.

Acute effect of an intervention with open and closed kinetic chain muscle strength exercises on postural control and muscle power in elderly people: A randomized clinical trial.

Introduction: Aging causes changes in stance control and muscle function. However, strength exercises can mitigate these negative effects. Intervention practices are classified into open kinetic chain (OKC) and closed kinetic chain (CKC), but it is unclear whether there are differences between them regarding muscle power and balance in the older people.

Influence of complexity of the task and the level of physical activity in the association between the muscular function and posture of older adults.

Introduction: Postural control involves the coordination of muscle synergies of lower limb for the performance of postural strategies. However, the relationship between muscle function and postural control of older adults with different levels of physical activity has not yet been fully elucidated. The aim of this study was to analyze the influence of muscle function of lower limb on postural control in tasks with disturbance in the visual and somatosensory systems of older adults with different levels of physical activity.

Influence of Physical Characteristics of Obstacles on the Locomotor Pattern of Older Adults at Higher Risk of Falling.

Objective: This study aimed to investigate the locomotor behavior of older adults with and without a history of falls as they avoided obstacles with different physical characteristics.

Methods: Twenty-one older adults participated in this study. The group was divided into higher risk of falling (n = 10) and lower risk of falling (n = 11).