Role of inflammation in a rat model of radiation retinopathy.

Radiation retinopathy (RR) is a major side effect of ocular tumor treatment by plaque brachytherapy or proton beam therapy. RR manifests as delayed and progressive microvasculopathy, ischemia and macular edema, ultimately leading to vision loss, neovascular glaucoma, and, in extreme cases, secondary enucleation. Intravitreal anti-VEGF agents, steroids and laser photocoagulation have limited effects on RR.

Assessing the containment efficiency of a microbiological safety cabinet during the simultaneous generation of a nanoaerosol and a tracer gas.

The intention of this article is to compare the containment performance of a Type II microbiological safety cabinet (MSC) confronted with the simultaneous generation of a saline nanoparticle aerosol and a tracer gas (SF(6)). The back dissemination coefficient, defined as the ratio of the pollutant concentration measured outside the enclosure to the pollutant flow rate emitted inside the enclosure, is calculated in order to quantify the level of protection of each airborne contaminant tested for three enclosure operating configurations: an initial configuration (without perturbations), a configuration exposing a dummy in front of the enclosure (simulation of an operator), and a configuration employing the movement of a plate in front of the enclosure (simulation of human movement). Based on the results of this study, we observed that nanoparticulate and gaseous behaviours are strongly correlated, thus showing the predominance of air-driven transport over particle-specific behaviour.

Crossover between Rayleigh-Taylor instability and turbulent cascading atomization mechanism in the bag-breakup regime.

The question of whether liquid atomization depends on instability dynamics (through refinements of Rayleigh-Plateau, Rayleigh-Taylor, or Kelvin-Helmholtz mechanisms) or on turbulent cascades, as suggested by Richardson and Kolmogorov, is still open. In this paper, experimental results reveal that both mechanisms are needed to explain the probability density functions (PDFs) of the droplets in a spray obtained from an industrial fan spray nozzle. Instability of Rayleigh-Taylor type controls the size of the largest droplets while the smallest droplets follow a PDF given by a turbulent cascading mechanism characterized by a log-Lévy stable law that has a stability parameter equal to 1.