Publications by authors named "N Rezvani"
Correction: Theobromine supplementation in combination with a low-calorie diet improves cardiovascular risk factors in overweight and obese subjects with metabolic syndrome: a randomized controlled trial.
Food Funct
August 2024
Article Synopsis
- The study investigates the effects of theobromine supplementation combined with a low-calorie diet on cardiovascular risk factors in overweight and obese individuals with metabolic syndrome.
- Results from the randomized controlled trial show that this combination improved various cardiovascular risk markers, contributing to better overall health.
- The findings suggest that theobromine could be a potential dietary supplement for enhancing the efficacy of weight-loss diets in managing metabolic syndrome.
Colorectal cancer (CRC) is known to develop due to the accumulation of both genetic and epigenetic alterations, resulting in the conversion of intestinal epithelial cells to malignant adenocarcinoma cells. Caudal type homeobox 1 () gene is a homeobox transcription factor and a selective tumour suppressor gene that is an important factor for the development of intestinal cells. This gene plays a role in the differentiation of intestinal epithelial cells, and its expression decreases in a number of cell lines derived from CRC, which suggests that a lack of expression is a risk factor for the development of colorectal carcinoma.
View Article and Find Full Text PDFBackground And Aims: Preeclampsia (PE) is a serious medical condition that usually causes high blood pressure and affects multiple organs. Considering the adverse effect of oxidative stress on the process of PE in pregnant women and regarding the role of the Nrf2 gene in placental oxidative pathways, this study was conducted to investigate the DNA methylation status of Nrf2 in PE and healthy pregnant women.
Materials And Methods: The present case-control study consisted of 70 PE and 70 healthy pregnant women.
The objective was to elucidate the potential epigenetic regulatory mechanism in expression in preeclampsia. promoter DNA methylation was evaluated in the placental tissue and blood of preeclamptic and normotensive pregnant women. and gene expression were assessed in placental tissue and peripheral blood mononuclear cells (PBMCs).
View Article and Find Full Text PDFBackground: Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs (miRNAs) are important epigenetic alterations that notably impact various physiological and pathological processes by acting as negative regulators of gene expression. Furthermore, they have a vital function in different types of cancers, including CRC.
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