Publications by authors named "N Relkin"
Bacterial biofilms, especially those associated with implanted medical devices, are difficult to eradicate. Curli amyloid fibers are important components of the biofilms formed by the Enterobacteriaceae family. Here, we show that a human monoclonal antibody with pan-amyloid-binding activity (mAb 3H3) can disrupt biofilms formed by Salmonella enterica serovar Typhimurium in vitro and in vivo.
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- The study focuses on the characteristics of 517 adults with hydrocephalus enrolled in the Adult Hydrocephalus Clinical Research Network over two years.
- The patients fall into four categories: transition (treated in childhood), unrecognized congenital (untreated congenital cases), acquired (related to known factors), and suspected idiopathic normal pressure hydrocephalus (iNPH, untreated, 65+ years).
- Findings reveal age disparities among groups, with the iNPH group showing the worst cognitive performance, while the unrecognized congenital group performed the best.