Publications by authors named "N Redeker"

Importance: Opioid use disorder (OUD) impacts millions of people worldwide. Prior studies investigating its underpinning neural mechanisms have not often considered how brain signals evolve over time, so it remains unclear whether brain dynamics are altered in OUD and have subsequent behavioral implications.

Objective: To characterize brain dynamic alterations and their association with cognitive control in individuals with OUD.

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Article Synopsis
  • Research indicates that structural and functional brain changes are linked to opioid use disorder (OUD), but earlier studies often had small participant groups, especially fewer women, and focused on single types of brain analysis.
  • This study aimed to use comprehensive brain imaging techniques, including T1-weighted MRI and resting-state fMRI, to better identify these brain alterations in OUD patients undergoing methadone treatment compared to healthy controls.
  • Results showed significant differences in brain volumes between the two groups, with OUD participants having smaller thalamus and temporal lobe sizes but larger brainstem and cerebellum volumes, and there were sex-based differences in the medial prefrontal cortex volumes.
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  • Researchers evaluated a digital sleep-alcohol intervention called Call it a Night (CIAN) using natural language processing with young adults who drink heavily (N=120).
  • Most participants preferred coaching from CIAN over control interventions, and while control groups found advice more helpful, overall satisfaction and adherence levels were high across all groups.
  • The study showed that sleep was a bigger motivator for participants than alcohol use, suggesting that improving sleep and wellness could be key factors for young adults in such interventions.
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Rates of specialist palliative care (SPC) vary among Veterans Affairs Medical Centers (VAMCs) for people with advanced heart failure (aHF). We evaluated the associations between facility rates of SPC reach and the quality of end of life (EOL) care received among this population. We conducted a retrospective cohort study among 3681 people with aHF who died in 83 VAMCs from 2018 to 2020.

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Background: Poor sleep contributes to adverse health in heart failure. However, studies are limited to isolated sleep characteristics.

Purposes: To evaluate changes in sleep health phenotypes after cognitive behavioral therapy for insomnia or attention control and associations between sleep health phenotypes, symptoms, stress, functional performance, and emergency department visits and hospitalizations.

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