Publications by authors named "N Ranisavljevic"
Ovarian response in preimplantation genetic testing for myotonic dystrophy type 1.
J Assist Reprod Genet
December 2024
Purpose: To evaluate ovarian stimulation response in couples undergoing preimplantation genetic testing (PGT-M) for myotonic dystrophy type 1 (DM1) METHODS: Retrospective, observational, multicentric study. Parameters of ovarian response and PGT-M outcomes were compared according to the DM1-affected patient (female or male). A total of 229 couples underwent at least one controlled ovarian hyperstimulation cycle for the PGT-M procedure.
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- The study aimed to understand patient preferences regarding pen injectors used in Assisted Reproduction Technology (ART) in France, focusing on treatment adherence.
- Using a discrete choice experiment with 155 women averaging 34 years old, researchers evaluated six attributes related to injector pens.
- Results indicated that patients highly valued features like dose confirmation, digital dose counters, multi-use capabilities, and the convenience of ready-to-use pens.
[Extension of the Use of Gametes in Intra-couple (EUGIC): How to use trans woman' spermatozoa?].
Gynecol Obstet Fertil Senol
September 2024
Article Synopsis
- The French Bioethics Law now allows lesbian couples and single women to access medically assisted reproduction, including the use of cryopreserved gametes, raising questions about new applications of these gametes among various couples, particularly those including transgender individuals.
- The study analyzes scenarios where a transgender woman's sperm is used within couples, rather than relying on gamete donation, highlighting existing practices and challenges faced by healthcare professionals.
- There are inconsistencies and legal gaps related to using a trans woman's sperm under the new EUGIC framework, resulting in complexities for medical practitioners and raising issues around the rights and interests of the unborn child.
Prospective multicenter observational real-world study to assess the use, efficacy and safety profile of follitropin delta during IVF/ICSI procedures (DELTA Study).
Géraldine Porcu-Buisson Chloé Maignien Nelly Swierkowski-Blanchard Catherine Rongières Noémie Ranisavljevic
Eur J Obstet Gynecol Reprod Biol
February 2024
Article Synopsis
- The study evaluated the use and effectiveness of follitropin delta in women undergoing IVF or ICSI, focusing on its safety and dosing patterns in clinical practice after one treatment cycle.
- Conducted in France across 14 centers, 248 women were treated, with 223 being analyzed; the study highlighted that a significant majority of patients followed a standardized dosing algorithm.
- Key findings included an average of 11.3 oocytes retrieved per patient, a clinical pregnancy rate of 35%, and an ongoing pregnancy rate of 29.6%, indicating good efficacy and safety of follitropin delta in IVF/ICSI treatments.