Publications by authors named "N Ramkumar"
Heart failure with preserved ejection fraction (HFpEF) has recently emerged as an insidiously and increasingly prevalent heart failure phenotype. HFpEF often occurs in the context of hypertension and obesity and presents with diastolic dysfunction, ventricular hypertrophy, and myocardial fibrosis. Despite growing study of HFpEF, the causal links between early metabolic changes, bioenergetic perturbations, and cardiac structural remodeling remain unclear.
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- The study analyzed how travel burden for surgical cancer care is affected by rural living, geographic choices, cancer type, and patient mortality outcomes using Medicare data from 2016-2018.
- It found that a significant percentage of cancer patients, particularly those in rural areas, chose to bypass their nearest surgical facility, leading to better survival outcomes post-surgery.
- The research highlights that understanding why rural patients bypass facilities could help improve cancer treatment results and address disparities in cancer care access.
Chronic kidney disease (CKD) is a progressive disorder marked by a decline in kidney function. Obesity and sedentary behavior contribute to the development of CKD, though mechanisms by which this occurs are poorly understood. This knowledge gap is worsened by the lack of a reliable murine CKD model that does not rely on injury, toxin, or gene deletion to induce a reduction in kidney function.
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