Objective: The study objective was to evaluate changes in abdominal adipose tissue and ectopic fat during pregnancy and their associations with gestational weight gain (GWG) in women with overweight/obesity.
Methods: This study was a secondary analysis of a randomized controlled trial. Magnetic resonance scans were performed during gestational week (GW) 15, GW 32, and around birth to measure abdominal subcutaneous (SAT) and visceral (VAT) adipose tissues, liver fat, and muscle fat.
Background: Maternal obesity and excessive weight gain during pregnancy are associated with higher birth weight and increased risk of childhood obesity.
Objective: This study investigated the effect of a high-protein and low-glycaemic-index (HPLGI) diet during pregnancy on offspring body composition and metabolic health.
Methods: We conducted a dietary intervention study in pregnant women with a pre-pregnancy BMI of 28-45 kg/m who were randomly assigned to an HPLGI diet or a moderate-protein moderate-glycaemic-index (MPMGI) diet.
J Clin Endocrinol Metab
December 2024
Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments.
View Article and Find Full Text PDFThe Danish Christmas Seal Homes offer a 10-week residential stay for socially vulnerable children. We aimed to examine the effects on body composition and cardiometabolic fitness variables of the standard program (SG) and whether substituting physical activity sessions with sessions from a football-based health education program is beneficial for the participants ("11 for Health"; SG+). Three hundred and nine children participated in SG (12.
View Article and Find Full Text PDFGestational diabetes mellitus (GDM) adversely affects offspring glucose homeostasis and risk of developing obesity. Here, we examined the association between glycemia in pregnant women with overweight or obesity without GDM and offspring metabolic health. Maternal fasting glucose concentrations and glucose 2-h after an oral glucose tolerance test (OGTT) were measured in 208 women with a pre-pregnancy body mass index (BMI) of 28-45 kg/m without GDM.
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