Publications by authors named "N R Stokes"

The objective of this study was to develop and to test the validity and reliability of a survey aimed to evaluate internal and external factors associated with college food insecurity. Researchers used a mixed methods approach to evaluate the College Perspectives around Food Insecurity survey. Survey items were constructed from interview data and assigned a social cognitive theory concept (environment, personal, or behavior).

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  • * A study demonstrates that metallothionein (MTH) immunohistochemistry (IHC) is a highly effective diagnostic method for WD, showing high sensitivity (91.20%) and perfect specificity (100%) in a cohort of 91 patients compared to control samples.
  • * MTH IHC could serve as a cost-effective and reliable screening tool for diagnosing WD in patients of different ages and disease stages, enhancing patient evaluation and management.
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The emergence of SARS-CoV-2 and seasonal outbreaks of other respiratory viruses highlight the urgent need for broad-spectrum antivirals to treat respiratory tract infections. Stimulator of interferon genes (STING) is a key component of innate immune signaling and plays a critical role in protection of the host against viral infections. Previously the STING agonist diABZI-4, a diamidobenzimidazole-based compound, demonstrated protection against SARS-CoV-2 both and .

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  • * The oligosaccharyltransferase (OST) complex, particularly the STT3A/B enzymes, plays a crucial role in this glycosylation and has emerged as a promising target for broad-spectrum antiviral drugs.
  • * The study highlights the balance between the antiviral potential of STT3A/B inhibitors, like NGI-1, and the need to assess their safety for humans, leading to the discovery of improved compounds that ensure both efficacy and lower toxicity risks.
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