Publications by authors named "N R Putarek"
Relative Frequency of Islet Autoimmunity in Children and Adolescents with Autoimmune Thyroid Disease.
J Clin Res Pediatr Endocrinol
November 2023
Objective: The aim of the present study was to investigate islet autoimmunity and susceptibility to type 1 diabetes (T1D) in children/adolescents with autoimmune thyroid disease (AITD, and in family members of AITD patients with islet autoimmunity.
Methods: Islet-cell cytoplasmic, glutamic-acid decarboxylase, and tyrosine-phosphatase autoantibodies (AAbs) were measured in 161 AITD patients [127 with autoimmune thyroiditis (AT); 34 with Graves’ disease (GD)], 20 family members of AITD patients with islet autoimmunity, and 155 age-matched controls.
Results: Islet autoimmunity was found in 10.
Article Synopsis
- Triple A syndrome is linked to mutations in the AAAS gene and often includes symptoms like low bone mineral density (BMD) that may go unnoticed.
- A study was conducted to investigate the frequency and potential causes of low BMD/osteoporosis in patients with this condition by measuring various bone and hormone markers.
- Findings revealed that many patients had low BMD for age at diagnosis, and while glucocorticoid therapy wasn't likely responsible for the osteoporosis, low adrenal androgens could be contributing factors.
Neonatal diabetes mellitus is a rare metabolic disorder with an estimated incidence of 1:300.000 to 400.000 newborns, and less than 50% of the neonates have permanent neonatal diabetes mellitus (PNDM).
View Article and Find Full Text PDFDuplication of the pituitary gland is a rare malformation. To the best of our knowledge, only 40 cases throughout the world have been reported previously. Due to associated severe developmental anomalies lots of these cases were diagnosed at autopsy.
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