Publications by authors named "N R Maddela"
Cellulases Production by Aspergillus unguis in Solid State Fermentation and Enzymatic Hydrolysis of Dilute Acid-Treated Groundnut Fodder.
Curr Microbiol
January 2025
Groundnut fodder was utilized as a bioresource for the production of cellulases through solid state fermentation (SSF). Aspergillus unguis was initially grown on modified groundnut fodder for cellulase production and the fodder was hydrolyzed by the crude cellulase extract into fermentable hydrolyzate. The highest titer of Filter paperase (FPase), Carboxymethyl cellulase (CMCase), β-glucosidase, and protein content were found to be 11.
View Article and Find Full Text PDFAntibiotic resistant bacteria and antibiotic resistance genes as contaminants of emerging concern: Occurrences, impacts, mitigations and future guidelines.
Sci Total Environ
November 2024
Article Synopsis
- Antibiotic resistance, fueled by the spread of antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria (ARBs), is a major global health issue linked to the overuse of antibiotics in medicine and agriculture.
- The environmental presence of ARGs, especially in places like municipal water and hospitals, poses serious health risks as they can be transferred to pathogens that affect humans.
- Current strategies to reduce ARGs and ARBs, while promising, face challenges, and future efforts should focus on better monitoring, international teamwork, and innovative solutions, including combination therapies and advanced oxidation techniques.
This study elucidated the influence on a partial denitrification (PD) system under 0-1 mg/L sulfamethoxazole (SMX) stress in a sequencing batch reactor. The results showed that the nitrite accumulation rate (NAR) significantly (P ≤ 0.01) decreased from 68.
View Article and Find Full Text PDFRecovery of enzymes such as FPase (filter paperase) or exoglucanase from fermented substrate is a sustainable approach in enzyme production; however, there is a scarcity of optimization studies in this field. The present study was aimed to standardize number of parameters (selection of solvent, solvent volume, soaking time, leaching conditions and number of washes) to extract maximum amount of FPase from fermented rice husk by Novel was first report from our lab on cellulases production in solid state fermentation (SSF). Among the tested solvents, citrate phosphate buffer (0.
View Article and Find Full Text PDFBackground: Keratomycosis is a form of infectious keratitis, an infection of the cornea, which is caused by fungi. This disease is a leading cause of ocular morbidity globally with at least 60 % of the affected individuals becoming monocularly blind.
Objective: This bibliometric analysis aimed to comprehensively assess the existing body of literature, providing insights of the evolution of keratomycosis research by identifying key themes and research gaps.