Real-world data on siponimod-related lymphopenia among people with secondary progressive multiple sclerosis.

Background: Siponimod-related lymphopenia in real-world clinical practice has implications for dose adjustment and infection risk.

Objective: To characterise siponimod-related lymphopenia in people with secondary progressive multiple sclerosis (pwSPMS).

Methods: This is a retrospective cohort of 188 pwSPMS.

Case report: Successful treatment of recurrent infection with bacteriophage therapy for patient suffering from chronic bacterial prostatitis.

Chronic Bacterial Prostatitis (CBP) is inflammation of the prostate caused by bacterial infection. An estimated 8.2% of men have prostatitis, most commonly under the age of 50.

Developing evidence-based guidelines for the safety of symptomatic drugs in multiple sclerosis during pregnancy and breastfeeding: A systematic review and Delphi consensus.

Background: Multiple sclerosis (MS) is frequently diagnosed in people of reproductive age, many of whom will become pregnant following diagnosis. Although many women report an improvement in symptoms and relapses during pregnancy, symptoms such as fatigue and spasticity are commonly reported and can worsen. Prescribing medications during pregnancy and breastfeeding presents unique challenges and guidance on the use of symptomatic therapies is limited.