Successful treatment of PASH syndrome with infliximab, cyclosporine and dapsone.

Background: The group of autoinflammatory syndromes associated with Pyoderma gangrenosum, Acne, and Suppurative Hidradenitis are poorly defined and difficult to control with currently available treatment modalities.

Objectives: We describe a patient with PASH syndrome and report about the successful multimodal treatment with infliximab, cyclosporine, and dapsone.

Methods: A review of the available literature to date about this group of autoinflammatory diseases was performed.

[Surgical reduction in benign symmetrical lipomatosis].

We report on a 50-year-old female patient suffering from benign symmetric lipomatosis of her upper arms, shoulders, neck, back, abdomen, and thighs. Concomitantly, we found hypertension, hyperuricemia, and hypertriglyceridemia. Since the patient complained of occasional pain in her upper arms and shoulders induced by work or pressure and suffered psychically from her deformity, we decided to reduce the fatty tissue of the upper arms surgically--with good cosmetic and functional results.

[Quantitative studies of the interaction of polyvinylpyrrolidone iodine and spermatozoa].

27 ejaculates were incubated together with polyvidone iodine diluted with physiological saline solution in various proportions. 10 minutes, 1 hour, 4 hours, and 20 hours later, we determined the percentages of mobile and viable spermatozoa in both the native and the incubated seminal fluid. 1% polyvidone iodine solution was totally spermicidal already after 10 minutes of incubation.

[Combined topical treatment of acne with erythromycin and tretinoin].

Vitamin A acid is the most effective comedolytic agent in the therapy of acne vulgaris. Antibiotics are suitable for the treatment of inflammatory lesions (papulo-pustules). Even topically applied, some antibiotics show a sufficient anti-inflammatory effect.