[Microbial "friend-foe" identification in human intestine microsymbiocenosis].

Aim: Development of methodical approach of evaluation of microbial "friend-foe" identification in human intestine microsymbiocenosis.

Materials And Methods: 9 bifidobacteria cultures (dominants) and 18 opportunistic microorganism strains (associants) isolated from patients during examination for intestine dysbiosis and identified by conventional methods were used. Evaluation of microbial "friend-foe" identification in microsymbiocenosis was performed by author developed technique that is based on determination of growth factors (GF), anti-lysozyme activity (ALA) and formation of biofilms (BFF) of associants co-incubated with exometabolites of dominants.

[Hemostatic studies in decompensated diabetes mellitus].

In 35 patients with decompensated diabetes mellitus the following hemostatic indices were studied: glycohemoglobin, prothrombin time, partial thromboplastin time, fibrin monomers (determined by protamine sulfate test), fibrinogen and platelet count. A statistically significant decrease of the prothrombin time (p less than 0.001) and of the partial thromboplastin time (p less than 0.

[The level of factor VIII/von Willebrand and inhibitors in diabetic retinopathy].

In 28 diabetics, classified into two groups according to the presence or absence of diabetic retinopathy, the following indices were examined: glycohemoglobin, factor VIII/von Willebrand, alpha-I-antitrypsin and alpha-2-macroglobulin. Factor VIII/von Willebrand and alpha-2-macroglobulin showed no changes in diabetes mellitus. Alpha-I-antitrypsin was statistically significantly decreased (p less than 0.

[Non-enzymatically glycosylated low-density lipoproteins in diabetes mellitus].

In 24 diabetic patients and 23 healthy persons the fatty metabolism was studied (cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol and glycosylated LD-lipoproteins). Iin diabetic patients the glycosylated low density lipoproteins travel from the cathode to the anode at a distance of 37-57 mm and in the control group they travel to a distance of 18-22 mm. In spite of the insignificant differences of cholesterol levels between the diabetics and the control and of the total cholesterol level being in normal ranges, the nonenzymatically glycosylated LD-lipoproteins are in greater quantity in the diabetics which is a predisposing factor for early atherosclerosis.

[Glycosylated proteins and various hemostatic indices in diabetic retinopathy].

The changes in the level of glycated proteins and some factors of coagulation were studied in 30 patients with diabetes mellitus--15 with and 15 without diabetic retinopathy. The mean level of glycoalbumin was elevated (2.9 +/- 0.