Publications by authors named "N Petousi"
Macrolides reduce exacerbations when added to inhaled therapy in severe asthma. However, there is little published evidence for effectiveness in patients treated with biologics. We conducted a retrospective audit of all patients who started azithromycin while on biologics in our centre.
View Article and Find Full Text PDFPurpose: Endocan is a biomarker of endothelial dysfunction, which is a precursor to cardiovascular disease. Obstructive sleep apnoea (OSA) is associated with elevated endocan levels but the effects of treatment on endocan levels in OSA are not fully established. We aimed to determine whether endocan levels could be detected by immunoassay and to determine the effect of supplemental oxygen during continuous positive airway pressure (CPAP) withdrawal on circulating endocan levels.
View Article and Find Full Text PDFPhenotyping of Severe Asthma in the Era of Broad-Acting Anti-Asthma Biologics.
J Allergy Clin Immunol Pract
April 2024
Article Synopsis
- - Severe asthma leads to high illness, death rates, and economic costs, and it's often unmanageable with traditional inhaled medications alone.
- - Biologic therapies are recommended for severe, uncontrolled asthma to reduce symptoms and improve quality of life, focusing on patients' unique clinical and inflammatory profiles.
- - Understanding different asthma phenotypes through clinical features and biomarker profiles is crucial for diagnosis, treatment selection, and monitoring, especially in the context of new biologic treatments.