Publications by authors named "N Palma"
Article Synopsis
- Early detection of pancreatic ductal adenocarcinoma (PDAC) is crucial for improving survival, but current methods like imaging and the CA19-9 blood test lack sensitivity for early-stage tumors.
- A study was conducted to identify a blood-based protein signature that performs better than CA19-9, analyzing approximately 3000 proteins and using machine learning to create multiple biomarker signatures.
- The new signatures showed significant improvements, achieving 84% sensitivity at 95% specificity, compared to CA19-9’s 53% sensitivity, and identified 41 promising biomarker candidates for further validation.
A simple method set for assessing biochemical changes associated with osmotic stress responses was developed using coffee (Coffea arabica L.) leaf disks. Stress was induced by polyethylene glycol (PEG) exposure.
View Article and Find Full Text PDFPortugal's real income per head grew by a factor of eight during the second half of the twentieth century, a period of fast convergence towards Western European living standards. We use a new sample of about 3,400 infants and children living in Lisbon to document trends in the prevalence of stunting and wasting between 1906 and 1994. We find that stunting and wasting fell quickly from around 1950, for both males and females.
View Article and Find Full Text PDFObjective: There is limited data about the impact of mood disorders treatment guidelines on clinical outcomes. The objective of this study was to investigate the impact of prescribers' adherence to the 2018 Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) treatment guidelines recommendations on the readmission rates of patients hospitalized for mania.
Method: A retrospective cohort of all individuals admitted due to acute mania to Kingston General Hospital, Kingston, ON, from January 2018 to July 2021 was included in this study.
Hepatocellular carcinoma (HCC) is the third most common cause of death from cancer worldwide. Therapeutic strategies are still challenging due to the high relapse rate after surgery and multidrug resistance (MDR). It is essential to better understand the mechanisms for HCC progression and MDR for the development of new therapeutic strategies.
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