Publications by authors named "N Paksoy"
This study conducted a comparative analysis of the concentration of the lead (Pb) in the albumen and yolk of eggs from domesticated chicken, quail, and duck, with a concurrent assessment of the potential carcinogenic and non-carcinogenic risks associated with the consumption of eggs sourced from Türkiye. A total of 78 poultry egg samples were gathered from breeding farms and farmers' markets situated in Şanlıurfa province. Lead concentrations were assessed through inductively coupled plasma optical emission spectrometry (ICP-OES).
View Article and Find Full Text PDFEfficacy and safety of sorafenib in adult metastatic osteosarcoma patients.
J Cancer Res Ther
April 2024
Background: There are limited data on the efficacy of targeted therapy in metastatic osteosarcoma. The goal of this study was to assess the effectiveness of sorafenib in adult patients with heavily pretreated metastatic osteosarcoma.
Method: Patients with metastatic osteosarcoma aged more than 18 years were assessed retrospectively.
Article Synopsis
- The study investigates how delivery and breastfeeding history affect breast cancer characteristics.
- The research involved 828 patients and found that women who have given birth (parous) generally get diagnosed with breast cancer at an older age compared to those who haven’t (nonparous).
- Additionally, women diagnosed during breastfeeding had larger tumors and worse disease characteristics than those who had never breastfed.
Background And Objective: The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) has been called into question on the basis of clinical trial data from the tyrosine kinase inhibitor (TKI) era. Comparative analyses of CN for patients treated with immuno-oncology (IO) versus TKI agents are sparse. Our objective was to compare CN timing and outcomes among patients who received TKI versus IO therapy.
View Article and Find Full Text PDFIntroduction: Patients with renal insufficiency, usually defined as those with creatinine clearance < 40 mL/min, were excluded from pivotal clinical trials, especially in studies involving nivolumab therapy in patients with renal cell carcinoma (RCC). The aim of the study is to evaluate the efficacy and safety of nivolumab in patients with metastatic RCC (mRCC) stratified according to creatinine clearance.
Material And Methods: Data from mRCC patients treated with nivolumab were retrospectively analyzed.