Stability and Release Kinetics of Natural Oil Microemulsions Containing Nicotinamide.

This research aimed to evaluate stability and release characteristics of nicotinamide-loaded microemulsions (MEs). Four MEs were prepared with Tween 80 as surfactant, Span 80 as cosurfactant, either virgin coconut oil or olive oil as oil phase, water as aqueous phase, and nicotinamide as an active ingredient. They were composed of 3% w/w nicotinamide and designated as MEC1-N, MEC2-N, MEO1-N, and MEO2-N.

Formulation of ascorbic acid microemulsions with alkyl polyglycosides.

Ascorbic acid microemulsions for topical application were developed. In this study, microemulsions were prepared using HLD (hydrophilic lipophilic deviation) concept to optimise the formulation. From this optimal formulation, the realisation of dilution ternary diagrams leads to obtain microemulsion zones.