Publications by authors named "N Padilla"
Aim: To describe the cortical brain development and full-IQ performance in middle school age children after extremely preterm (EPT) birth considering discrete white matter abnormalities (WMA). In addition, to assess possible early motor predictors of cortical brain development and full-IQ in children born EPT with and without discrete WMA diagnosed at 10 years.
Methods: T1-weighted MRI images from fifty-one children born before 27 weeks' gestation and 40 full-term born controls (M=10.
Article Synopsis
- The study aimed to evaluate how low-grade intraventricular hemorrhage (IVH) affects health outcomes in extremely preterm (EPT) children compared to those without IVH.
- Conducted on 103 EPT children born between 2004-2007 in Stockholm, the study compared neonatal morbidities and neurodevelopmental assessments at 10 and 12 years, respectively.
- Results showed that while children with low-grade IVH had more health complications during the neonatal period, there were no significant differences in brain volume or neurodevelopmental outcomes at later ages.
Article Synopsis
- - The study analyzed brain dynamics in 10 individuals with pharmacoresistant focal epilepsy and 30 healthy controls using resting-state functional MRI, focusing on how seizures start and spread.
- - Findings revealed significant changes in global brain connectivity, with increased integration and flexibility, and specific regions showing paradoxical decreases in ignition within the seizure onset zone.
- - The results contribute to a better understanding of epilepsy mechanisms and may help in creating diagnostic tools and therapies for seizure management.
Article Synopsis
- A new financial navigation (FN) intervention was developed and tested to help cancer patients dealing with financial toxicity, using a comprehensive screening tool to identify those in distress.
- In the study involving 50 patients at the North Carolina Basnight Cancer Hospital, all participants screened positive for financial distress, and 46 patients completed the intervention, which included consultations with a trained financial navigator.
- Results showed a significant improvement in perceived financial toxicity, with average scores rising from 6.4 to 13.3 after the intervention, and 96% of participants received financial assistance, indicating the intervention's effectiveness and high acceptance.
Brain activity during working memory in patients with autoimmune Addison's disease.
Psychoneuroendocrinology
December 2024
Article Synopsis
- Autoimmune Addison's disease (AAD) requires daily hormone replacement for cortisol and aldosterone, but current treatments often lead to unstable cortisol levels that may impact brain function.
- A study compared working memory function in young adults with AAD to healthy controls, using MRI scans during cognitive tasks, and found no significant differences in performance or brain activity between the two groups.
- The researchers acknowledge that variations in the AAD patient population could affect the results, suggesting the need for larger controlled studies to better understand the long-term impact of AAD on brain health.