Publications by authors named "N P Sugoniaeva"

The characteristics of the toxic effect of rose-stained grain of fusarial and non-fusarial nature, as well as the grain experimentally challenged with the toxic strain Fusarium sporotrichiella 53315, were studied basing on the analysis of morphological changes in the internal organs of young rat given orally extracts from the samples studied. The tissue aging processes under the effect of the extract doses producing no irreversible pathologic changes were investigated. It was shown that the extracts of rose-stained natural grain, fusarial and without signs of fusaridiosis, produced similar pathological changes in the morphological structures of the organs in the young rats, the toxicity grew with the increase of the per cent of rose-stained grain.

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The content of serum IgG, IgM and IgG was studied in rabbits at varying times of oral sensitization of animals before and after administration of the resolving dose of food protein. The content of IgG was found to be reduced on the 19th-21st day of sensitization. Meanwhile the content of IgA increased on the 24th day of oral sensitization.

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The frequency of distribution of DNA-synthesizing cells in the intestinal crypt, in the gland of the fundus of the stomach and adrenocortical substance was studied in rats in terms of the age aspect. The common features of cytologic organization of the test organs are as follows: irregularity in the location of DNA synthesis and mitotic zones along the linear structure of an organ; density of the features investigated in the structure of an organ depending on the cell position and animal age; shortening with age of the zone of cell division in the hepatic balk, gastric glands and intestinal crypt.

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