A new species, , was described from the tropical region of the Western Ghats of Maharashtra, India based on morphological characteristics and molecular phylogenetic analysis. is characterised by its yellowish brown to reddish brown granular scales on the pileus, stipe apex exudes colourless drops, broadly ellipsoid to ellipsoid to ovoid basidiospores, clavate to cylindrical, catenulate cheilocystidia with subglobose to cylindrical ante-terminal elements. Further, the molecular markers nrITS and nrLSU sequence data analyses of with their sister taxa revealed the distinct phylogenetic position of the new species.
View Article and Find Full Text PDFThe isoquinoline core is present in one of the largest subsets of bioactive natural products. The multifunctional isoquinoline core exerts diverse bioactivity, resulting in the development of numerous isoquinoline-based drugs and molecules that are currently under clinical trials. We developed a new approach for phosphite-mediated [1,2] alkyl migration for an overall -C-H alkylation -alkylation of isoquinoline.
View Article and Find Full Text PDFExtraocular muscle (EOM) enlargement occurs in both acromegaly and Graves' disease, but the degree and pattern of enlargement have not been directly compared in these patient groups. This study investigated whether acromegaly and Graves' orbitopathy (GO) are associated with different patterns of EOM enlargement at the time of diagnosis. Retrospective cohort.
View Article and Find Full Text PDFPatellar fractures can lead to extensor mechanism dysfunction if not repaired properly, impacting knee function and mobility, and this complication can be challenging to manage, especially in cases where previous surgical interventions have failed. The aim of this study was to evaluate the functional outcome of the salvaged extensor mechanism in patella fracture non-union using Krakow sutures in a 61-year-old female patient who presented with knee pain, reduced flexion, and a 40-degree extension lag after two previous patellar fracture surgeries using tension band wiring resulted in non-union. Despite rehabilitation attempts, her knee function remained compromised.
View Article and Find Full Text PDFAccurate blood pressure (BP) measurement is essential for detecting, diagnosing, treating, and monitoring hypertensive individuals. This qualitative improvement initiative study is aimed at improving adherence to standardised BP measurement protocols in an urban primary health centre in Delhi, India. This study was conducted using a checklist based on World Health Organisation (WHO) guidelines.
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