[Influence of the Parameter "The Rate of Administration" During the Test "Abnormal Toxicity" on Quality Control of Ceftriaxone an Antibiotic of the Cephalosporin Group].

The influence of the rate of administration was examined during the test "Abnormal toxicity" on the quality control of ceftriaxone in a comparative experimental study on the basis of the methodologies Rus. Ph. XII and Eur.

[Organic solvents for determination of bacterial endotoxin index in water-insoluble pharmaceutical substances].

Substances for manufacture of parenteral drugs require control by the "Bacterial Endotoxin" (BE) index with the LAL-test. The aim of the study was to show possible applicability of organic solvents in BE determination by the gel-thromb test in case of water-insoluble pharmaceutical substances. The results confirmed that ethyl alcohol practically had no effect on the endotoxin activity.