Evaluation of renal cortical perfusion by noninvasive power Doppler ultrasound during vascular occlusion and reperfusion.

Background: Urine output, a frequently used resuscitation end point, is presumed to represent renal cortical perfusion. However, no noninvasive method for direct measurement of renal perfusion exists. Power Doppler ultrasound (PDUS) is a method that reportedly is sensitive to low-velocity and microvascular blood flow and can depict it.

Integra as a dermal replacement in a meshed composite skin graft in a rat model: a one-step operative procedure.

Background: Current use of Integra, the collagen-based dermal analogue, requires a two-step grafting procedure to achieve wound closure with an "ultrathin" autograft.

Methods: A one-step operative procedure of meshed composite skin graft (MCSG) using Integra as a dermal template for a meshed split thickness autograft was developed in rats. The silicon layer of Integra was removed, the resulting dermal analogue was meshed (1:1.

Direct current reduces accumulation of Evans Blue albumin in full-thickness burns.

Background: Application of direct current (DC) to a burn wound limits extension of the zone-of-stasis and reduces wound tissue edema.

Objective: To study the effects of DC on extravasation of plasma proteins after burn by using Evans blue (EB) as a marker of plasma albumin.

Materials And Methods: Male Sprague-Dawley rats with 20% total body surface area full-thickness scalds (100 degrees C/10 sec) were used as the experimental model.

Optimized mesh expansion of composite skin grafts in rats treated with direct current.

Background: The purpose of this study was to determine the optimum autoepidermal and allodermal expansion ratio of each component of a meshed composite skin graft (MCSG) that would lead to successful healing.

Methods: Male Sprague-Dawley rats were used as hosts of the MCSG and donors of autologous tissue. Male ACI rats were used as donors of allodermis.

Direct current reduces plasma protein extravasation after partial-thickness burn injury in rats.

Objective: To observe the effect of 40 microA direct current (DC) on plasma albumin extravasation after burn injury.

Design, Materials, And Methods: Silver-nylon wound dressings were used as anodes (-) on anesthetized male Sprague-Dawley rats with 20% total body surface partial-thickness scald burns. Burned rats with no treatment, or treated with silver-nylon dressing without current, were used as controls.