The effect of continuous positive airway pressure therapy on early atherosclerosis in patients with severe obstructive sleep apnea-hypopnea syndrome.

Purpose: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is the most common sleep-related breathing disorder. Longer term, repeated episodes of hypercapnia and hypoxemia during sleep are associated with inflammatory and atherosclerosis-related factors. The aim of this study was to explore the effect of continuous positive airway pressure (CPAP) therapy on cerebral vasoreactivity and early atherosclerosis in patients with severe OSAHS.

Potential and real dangers of the chemical warfare agents use during the full-scale invasion into Ukraine.

Objective: Aim: To analyze modern threats of the use of chemical warfare agents on the line of contact during the full-scale invasion into Ukraine.

Patients And Methods: Materials and Methods: The study was carried out with the use of theoretical methods (information retrieval, analytical, descriptive, generalization, system analysis and information synthesis) and the construction of trends with the identification of the coefficient of determination.

Results: Results: Most of damage cases of the military men of the Armed Forces of Ukraine were caused by the enemy's use of such groups of chemical warfare agents with an irritating effect as lacrimators and sternites, more specifically K-51 grenades with chloropicrin (PS) and 2-chlorobenzalmalononitrile (CS), RGR grenade with 2-chlorobenzalmalononitrile (CS) and RG-Vo (862-3-23) grenades with chloroacetophenone (CN).

A CASE REPORT OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS.

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Charg-Strauss syndrome or allergic granulomatous angiitis, is defined as a systemic vasculitis identified by the presence of allergic rhinitis and/or asthma, correlated with the presence of marked eosinophilia in the peripheral blood, eosinophilic infiltration of various organs with extensive areas of necrosis, eosinophilic, giant cell vasculitis of vessels of small and medium caliber, as well as perivascular and interstitial necrotizing granulomas. The frequency is 10 - 14 cases per million in the adult population. The average time interval from the onset of the disease to establishing the diagnosis is 49.

National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities.

Brain metastases are an increasing global public health concern, even as survival rates improve for patients with metastatic disease. Both metastases and the sequelae of their treatment are key determinants of the inter-related priorities of patient survival, function, and quality of life, mandating a multidimensional approach to clinical care and research. At a virtual National Cancer Institute Workshop in September, 2022, key stakeholders convened to define research priorities to address the crucial areas of unmet need for patients with brain metastases to achieve meaningful advances in patient outcomes.

Mercury and amino acid content relations in northern pike (Esox lucius) in subarctic lakes along a climate-productivity gradient.

Mercury is a highly toxic element for consumers, but its relation to amino acids and physiology of wild fish is not well known. The main aim of this study was to evaluate how total mercury content (THg) of northern pike (Esox lucius) is related to amino acids and potentially important environmental and biological factors along a climate-productivity gradient of ten subarctic lakes. Linear regression between THg and sixteen amino acids content [nmol mg dry weight] from white dorsal muscle of pike from these lakes were tested.