Publications by authors named "N P Kintyukhina"

Article Synopsis
  • Chronic mixed blepharitis is a common eye condition, making up 51.7% of ophthalmic diseases, and LDF (laser Doppler flowmetry) can help diagnose its early inflammatory signs to prevent complications like dry eye disease.
  • A study involving 23 patients with chronic mixed blepharitis and 18 healthy volunteers evaluated the effectiveness of LDF in detecting microcirculatory changes in the eyelid skin.
  • Results indicated that LDF has high sensitivity and specificity in identifying eyelid damage related to chronic mixed blepharitis, making it a useful diagnostic tool alongside other clinical methods.
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This article reviews modern functional and instrumental examination methods included in the diagnostic algorithm for dry eye disease. The described methods can serve as an objective criterion for the effectiveness of the therapy.

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Unlabelled: The expanding range of diagnostic instrumental methods allows an in-depth study of the morphological and functional state of the eyelids, which is the basis for determining the strategy for the treatment of chronic blepharitis and subsequent timely supplementation and altering of its algorithm.

Purpose: To substantiate the repeated courses of invasive treatment of chronic blepharitis based on morphological and functional studies.

Material And Methods: The study included 45 patients (90 eyes) with chronic mixed blepharitis.

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After allogeneic hematopoietic stem cell transplantation (allo-HSCT), various eye diseases are detected in 30-60% of patients, with chronic graft-versus-host reaction - in 50-90% of patients. Among the complications, the most frequent is damage to the eye surface and eyelids. The article presents a clinical case of successful minimally invasive treatment of chronic posterior blepharitis in a patient who has undergone allogeneic hematopoietic stem cell transplantation.

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The most effective method of treating chronic blepharitis - a disease with multifactorial pathogenesis requiring an individual approach - is a combination of remedial measures that addresses eyelids hygiene and includes medicated and device therapy.

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