Publications by authors named "N P Burmantova"

Article Synopsis
  • The study analyzed how the sympathoadrenal system responds to exercise in healthy males versus patients with postinfarction cardiosclerosis and angina pectoris, focusing on catecholamine levels in urine.
  • It was found that patients exhibited a greater increase in catecholamine levels during exercise compared to healthy individuals, indicating hyperreactivity of the sympathoadrenal system.
  • A dose of anaprilin (40 mg) effectively reduced this overreaction to exercise and improved exercise tolerance, suggesting a dysfunction in the system for patients and highlighting the potential protective benefits of beta-blockers in coronary heart disease.
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The influence of sunflower and olive oils and their combination with cholesterol on the activity of lysosomal hydrolases and lipid peroxidation (LPO) in the mucosa of the mouth and jejunum was studied. It was shown that in the presence of cholesterol in the oral mucosa the activity of N-acetylhexosaminidase increased and there was a tendency to decreasing cathepsin D and acetyl esterase activity, and LPO processes were found to be suppressed. Cathepsin D and B activities in the jejunum mucosa increased in response to cholesterol administration.

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The study was undertaken to examine 68 healthy males and 34 patients with Functional Class I coronary heart disease. The insulin test (fasting intravenous simple insulin, 0.15 U/kg body weight, was given in the morning) was performed.

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In rats receiving a protein-poor diet for 60 days (4% caloric share of casein) the activity of beta-galactosidase, beta-N-acetyl glucose aminidase, acid proteinases, acid phosphatase, acetyl estherase, catalase, glutathione reductase, monoamine oxidase (MAO), glucose-6-phosphate dehydrogenase, and the content of malonic dialdehyde (MDA) were measured in the oral cavity mucosa. The authors observed the significant increase in MAO activity, and decrease in activities of beta-N-acetyl glucose aminidase, acetyl estherase, catalase, glutathione reductase, increased MDA contents. The changes in enzymatic activities had, to a several extent, an adaptive nature and were related to their reduced biosynthesis.

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